Chemical composition and biological activity of Salvia officinalis essential oil


Authors: Miroslava Kačániová, Lucia Galovičová, Veronika Valková, Hana Ďuranová, Petra Borotová, Jana Štefániková, Nenad L. Vukovic, Milena Vukic, Simona Kunová, Soňa Felsöciová, Katarína Miklášová, Tatsiana Savitskaya and Dmitrij Grinshpan

Volume/Issue: Volume 24: Issue 2

Published online: 02 Dec 2021

Pages: 81 - 88



The study was aimed at analyzing chemical composition, and biological and antibiofilm activity of Salvia officinalis L. essential oil (EO) with MALDI-TOF MS Biotyper. The main compounds of S. officinalis EO were a-thujone 24.6%, camphor 20.6%, 1,8-cineole 12.1%, and a-humulene 5.8%. Free radical scavenging activity was medium high. The highest antimicrobial activity was observed against Bacillus subtilis. Changes in the biofilm structure confirmed the inhibitory action of S. officinalis and the most pronounced effect was observed in B. subtilis biofilm. The highest inhibition in situ in antimicrobial activity was 78.45% at 125 µ.L−1 on apple for B. subtilis.

Keywords: sage essential oil, antimicrobial activity, antibiofilm profile, flavonoids, microorganisms



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